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Medical Diagnosis

6 items

RESEARCHarXiv CS.LG·5d ago

Early Detection of Alzheimer's Disease Using Explainable Machine Learning on Clinical Biomarkers: A Multi-Class Classification Study Using the Alzheimer's Disease Neuroimaging Initiative (ADNI) Dataset

An XGBoost classifier was developed using clinical features from the ADNI dataset for multi-class detection of normal cognition, mild cognitive impairment, and Alzheimer's disease. The model achieved a high mean macro AUC of 0.983 and an accuracy of 0.944, with SHAP values providing feature explainability.

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RESEARCHarXiv CS.LG·21d ago

Forecasting Medium-Horizon Alzheimer's Disease Progression: Residual Gap-Aware Transformers for 24-Month CDR-SB Change from ADNI Clinical and Biomarker Histories

This paper introduces a residual gap-aware transformer for forecasting 24-month Alzheimer's disease progression using ADNI clinical and biomarker histories. The research analyzes changes in CDR-SB scores, anchoring samples at mild cognitive impairment visits.

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